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Modulation of Gut Microbiota in Pathological States

Yulan Wang, Baohong Wang, Junfang Wu, Xiangyang Jiang, Huiru Tang, Ole H. Nielsen

Engineering 2017, Volume 3, Issue 1,   Pages 83-89 doi: 10.1016/J.ENG.2017.01.013

Abstract: Our gut microbiota evolves with us and plays a pivotal role in human health and disease.The gut microbiota may be linked to malignancies such as gastric cancer and colorectal cancer., the aim of this review is to provide the reader with an updated overview of the importance of the gutThe concept of altering the gut community by microbial intervention in an effort to improve health isThus, the removal of harmful organisms and the enrichment of beneficial microbes may protect our health

Keywords： Gut microbes     Diseases     Microbial modulation    

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Gut microbial balance and liver transplantation: alteration, management, and prediction

Xinyao Tian, Zhe Yang, Fangzhou Luo, Shusen Zheng

Frontiers of Medicine 2018, Volume 12, Issue 2,   Pages 123-129 doi: 10.1007/s11684-017-0563-2

Abstract: Importantly, the resulting alteration of gut microbiota aggravates graft dysfunctions during the processThis article reviews the research progress for gut microbial alterations and liver transplantation.Especially, this work also evaluates research on the management of gut microbial alteration and the predictionIn addition, we propose possible directions for research on gut microbial alteration during liver transplantation

Keywords： gut microbial balance     liver transplantation     ischemia–reperfusion     acute rejection    

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Integrated analysis of gut microbiome and host immune responses in COVID-19

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 263-275 doi: 10.1007/s11684-022-0921-6

Abstract: Emerging evidence indicates that the gut microbiome contributes to the host immune response to infectiousWe identified the abundance of some gut microbes altered post-SARS-CoV-2 infection and related to diseaseWe further analyzed the correlation between the abundance of gut microbes and host responses, and obtainedMoreover, a number of metabolic pathways in gut microbes were also found to be differentially enrichedTogether, our study highlighted a potential regulatory role of severity related gut microbes in the immune

Keywords： COVID-19     SARS-COV-2     gut microbiome     immune response    

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The main anammox-based processes, the involved microbes and the novel process concept from the application

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 7, doi: 10.1007/s11783-021-1487-1

Abstract:

• The PNA, denitratation/anammox, and DAMO/anammox process are reviewed together.

Keywords： Anammox     Nitritation     Denitratation     Denitrifying anaerobic methane oxidation     Mainstream wastewater    

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Biogenic palladium prepared by activated sludge microbes for the hexavalent chromium catalytic reduction

Luman Zhou, Chengyang Wu, Yuwei Xie, Siqing Xia

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 2, doi: 10.1007/s11783-019-1206-4

Abstract: • Pd nanoparticles could be reduced and supported by activated sludge microbes. • The effect of biomasson Pd adsorption by microbes is greater than Pd reduction. • More biomass reduces Pd particle size,In this study, Pd nanoparticles (PdNPs) were generated through enzymatic recovery by microbes of activatedThe XRD and TEM-EDX results confirmed the existence of PdNPs associated with microbes (bio-Pd).

Keywords： Palladium nanoparticles     Activated sludge     Hexavalent chromium    

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Mechanistic and therapeutic advances in non-alcoholic fatty liver disease by targeting the gut microbiota

Ruiting Han, Junli Ma, Houkai Li

Frontiers of Medicine 2018, Volume 12, Issue 6,   Pages 645-657 doi: 10.1007/s11684-018-0645-9

Abstract: disease because of the intricate role of gut microbiota in maintaining human health and disease formationMoreover, gut microbiota is even regarded as a “metabolic organ” that play complementary roles to thatAs a result, gut microbiota have been emerging as a novel therapeutic target for NAFLD by manipulatingIn this review, we summarized the most recent advances in gut microbiota-mediated mechanisms, as wellas gut microbiota-targeted therapies on NAFLD.

Keywords： gut microbiota     NAFLD     obesity     insulin resistance     bile acids     probiotic    

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Synthetically engineered microbes reveal interesting principles of cooperation

Michael D. Dressler,Corey J. Clark,Chelsea A. Thachettu,Yasmine Zakaria,Omar Tonsi Eldakar,Robert P. Smith

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 1,   Pages 3-14 doi: 10.1007/s11705-016-1605-z

Abstract: By engineering rationally controlled and modulatable behavior into microbes, we have increased our overallOverall, the use of engineered cooperative microbes has allowed the field to verify existing, and develop

Keywords： synthetic biology     engineered bacteria     cooperation     cheater     quorum sensing    

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Calorie restriction and its impact on gut microbial composition and global metabolism

Xiaojiao Zheng, Shouli Wang, Wei Jia

Frontiers of Medicine 2018, Volume 12, Issue 6,   Pages 634-644 doi: 10.1007/s11684-018-0670-8

Abstract: In the present review, we focus on the general effect of CR on gut microbiota composition and globalResults showed that probiotic and butyrate-producing microbes increased their relative abundance, whereasAnalyses of the gut microbial and host metabolisms revealed that most host microbial co-metabolites wereThe observed phenotypes and the further verification of the direct link between gut microbiota and metabolomeThus, improved gut microbiota composition and metabolome are potential biomarkers for determining the

Keywords： caloric restriction     gut microbiota     metabolome    

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ADT-OH improves intestinal barrier function and remodels the gut microbiota in DSS-induced colitis

Frontiers of Medicine   Pages 972-992 doi: 10.1007/s11684-023-0990-1

Abstract: Owing to the increasing incidence and prevalence of inflammatory bowel disease (IBD) worldwide, effective and safe treatments for IBD are urgently needed. Hydrogen sulfide (H2S) is an endogenous gasotransmitter and plays an important role in inflammation. To date, H2S-releasing agents are viewed as potential anti-inflammatory drugs. The slow-releasing H2S donor 5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione (ADT-OH), known as a potent therapeutic with chemopreventive and cytoprotective properties, has received attention recently. Here, we reported its anti-inflammatory effects on dextran sodium sulfate (DSS)-induced acute (7 days) and chronic (30 days) colitis. We found that ADT-OH effectively reduced the DSS-colitis clinical score and reversed the inflammation-induced shortening of colon length. Moreover, ADT-OH reduced intestinal inflammation by suppressing the nuclear factor kappa-B pathway. In vivo and in vitro results showed that ADT-OH decreased intestinal permeability by increasing the expression of zonula occludens-1 and occludin and blocking increases in myosin II regulatory light chain phosphorylation and epithelial myosin light chain kinase protein expression levels. In addition, ADT-OH restored intestinal microbiota dysbiosis characterized by the significantly increased abundance of Muribaculaceae and Alistipes and markedly decreased abundance of Helicobacter, Mucispirillum, Parasutterella, and Desulfovibrio. Transplanting ADT-OH-modulated microbiota can alleviate DSS-induced colitis and negatively regulate the expression of local and systemic proinflammatory cytokines. Collectively, ADT-OH is safe without any short-term (5 days) or long-term (30 days) toxicological adverse effects and can be used as an alternative therapeutic agent for IBD treatment.

Keywords： inflammatory bowel disease     ADT-OH     intestinal permeability     gut microbiota    

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From gut changes to type 2 diabetes remission after gastric bypass surgeries

Bing Li, Xinrong Zhou, Jiarui Wu, Huarong Zhou

Frontiers of Medicine 2013, Volume 7, Issue 2,   Pages 191-200 doi: 10.1007/s11684-013-0258-2

Abstract:

Increasing evidence suggests that the gut may influence the host’s metabolism and ultimatelyWe review the evidence on the relationship between the gut and T2DM remission after gastric bypass surgery, and discuss the potential mechanisms underlying the above relationship: gut anatomical rearrangement, microbial composition changes, altered gut cells, and gut hormone modulation.

Keywords： gastric bypass     T2DM     gut    

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Analysis and Application of Microbes Diversification in Wa stewaterAerobic Biological Treatment

Zhang Lei,Liu Na,Cui Hongtao,Zhou qiang,Lu Xiaoguang, Zhao Zhibin

Strategic Study of CAE 2007, Volume 9, Issue 11,   Pages 209-212

Abstract: article simply introduces some kinds of microbe in different phase, and simply analyses the cause of microbes

Keywords： wastewater from printing and dyeing     aerobic biological treatment     microbes diversification    

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Pien Tze Huang Protects Against Non-Alcoholic Steatohepatitis by Modulating the Gut Microbiota and Metabolites

Xianyi Zeng,Xiang Zhang,Hao Su,Hongyan Gou,Harry Cheuk-Hay Lau,Xiaoxu Hu,Ziheng Huang,Yan Li,Jun Yu,

Engineering doi: 10.1016/j.eng.2022.10.010

Abstract: Through the metagenomic sequencing of stool samples, we found that PTH administration restored the gutIn addition, PTH restored the gut barrier function in mice with steatohepatitis, as evidenced by reducedWe further confirmed that an intact gut microbiota is necessary for PTH to exhibit anti-steatohepatitisIn conclusion, PTH protects against steatohepatitis development by modulating the gut microbiota and

Keywords： Pien Tze Huang     Non-alcoholic steatohepatitis     Gut barrier function     Gut microbiota    

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Biodegradation of waste refrigerator polyurethane by mealworms

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 3, doi: 10.1007/s11783-023-1638-8

Abstract:

● Waste refrigerator polyurethane (WRPU) was ingested and biodegraded by mealworms.

Keywords： Waste refrigerator polyurethane     Mealworms     Biodegradation     Carbon balance     Gut microorganism    

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Gut microbiota and its implications in small bowel transplantation

Chenyang Wang, Qiurong Li, Jieshou Li

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 239-248 doi: 10.1007/s11684-018-0617-0

Abstract:

The gut microbiota is mainly composed of a diverse population of commensal bacterial species and playsThe influence of the gut microbiota on solid organ transplantation has recently been recognized.bowel transplantation (SBT) is closely associated with the alterations in microbial patterns in the gutFurthermore, we explored the potential of the gut microbiota as a microbial marker and/or therapeuticGiven that current research on the gut microbiota has become increasingly sophisticated and comprehensive

Keywords： gut microbiota     small bowel transplantation     acute rejection     chronic rejection     mucosal immunity     biomarker    

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EFFECT OF SOLARIZATION TO KILL BRADYSIA CELLARUM ON CHINESE CHIVE GROWTH AND SOIL MICROBIAL DIVERSITY

Frontiers of Agricultural Science and Engineering 2022, Volume 9, Issue 1,   Pages 52-62 doi: 10.15302/J-FASE-2021402

Abstract:

Bradysia cellarum Frey (Diptera: Sciaridae) is an important subterranean pest and is especially damaging to Chinese chive. An effective and more environmentally safe method than pesticides is needed for its control. The efficacy of B. cellarum control, growth of Chinese chive and soil microbial diversity were investigated after uae of soil solarization to exterminate this insect pest. The results show that on the first day after soil solarization 100% control of B. cellarum was achieved. Growth of Chinese chive was lower in solarized plots than in control plots over the first 10 d after treatment. Chive growth in solarized plots increased subsequently to match that in the control plots. Moreover, the soil microbial community diversity in the treatment group decreased initially before gradually recovering. In addition, the abundance of beneficial microorganisms in the genus Bacillus and the phyla Proteobacteria, Chloroflexi and Firmicutes increased significantly. Soil solarization is therefore practical and worthy of promotion in Chinese chive-growing regions.

 

Keywords： Bradysia cellarum / Chinese chive / control / soil microbes / soil solarization    

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Title Author Date Type Operation

Modulation of Gut Microbiota in Pathological States

Yulan Wang, Baohong Wang, Junfang Wu, Xiangyang Jiang, Huiru Tang, Ole H. Nielsen

Journal Article

Gut microbial balance and liver transplantation: alteration, management, and prediction

Xinyao Tian, Zhe Yang, Fangzhou Luo, Shusen Zheng

Journal Article

Integrated analysis of gut microbiome and host immune responses in COVID-19

Journal Article

The main anammox-based processes, the involved microbes and the novel process concept from the application

Journal Article

Biogenic palladium prepared by activated sludge microbes for the hexavalent chromium catalytic reduction

Luman Zhou, Chengyang Wu, Yuwei Xie, Siqing Xia

Journal Article

Mechanistic and therapeutic advances in non-alcoholic fatty liver disease by targeting the gut microbiota

Ruiting Han, Junli Ma, Houkai Li

Journal Article

Synthetically engineered microbes reveal interesting principles of cooperation

Michael D. Dressler,Corey J. Clark,Chelsea A. Thachettu,Yasmine Zakaria,Omar Tonsi Eldakar,Robert P. Smith

Journal Article

Calorie restriction and its impact on gut microbial composition and global metabolism

Xiaojiao Zheng, Shouli Wang, Wei Jia

Journal Article

ADT-OH improves intestinal barrier function and remodels the gut microbiota in DSS-induced colitis

Journal Article

From gut changes to type 2 diabetes remission after gastric bypass surgeries

Bing Li, Xinrong Zhou, Jiarui Wu, Huarong Zhou

Journal Article

Analysis and Application of Microbes Diversification in Wa stewaterAerobic Biological Treatment

Zhang Lei,Liu Na,Cui Hongtao,Zhou qiang,Lu Xiaoguang, Zhao Zhibin

Journal Article

Pien Tze Huang Protects Against Non-Alcoholic Steatohepatitis by Modulating the Gut Microbiota and Metabolites

Xianyi Zeng,Xiang Zhang,Hao Su,Hongyan Gou,Harry Cheuk-Hay Lau,Xiaoxu Hu,Ziheng Huang,Yan Li,Jun Yu,

Journal Article

Biodegradation of waste refrigerator polyurethane by mealworms

Journal Article

Gut microbiota and its implications in small bowel transplantation

Chenyang Wang, Qiurong Li, Jieshou Li

Journal Article

EFFECT OF SOLARIZATION TO KILL BRADYSIA CELLARUM ON CHINESE CHIVE GROWTH AND SOIL MICROBIAL DIVERSITY

Journal Article